2026 CTR Non-Proliferation Programing

DOS-ISN DFOP0017675
Posted: Jan 08, 2026 12:00:00 AM EST
Closes: 03/06/2026

Funding Information

Estimated Total Funding
$105,000,000
Award Ceiling
$10,000,000
Award Floor
$250,000
Expected Number of Awards
50

Description

The Office of Cooperative Threat Reduction (CTR) is a key component of the Department’s and ACN’s efforts to advance the Administration’s top national security and foreign policy objectives in a cost-effective and impactful manner. CTR uses programming and training with foreign partners to advance President Trump’s America First Investment Policy (NSPM-3) and America’s AI Action plan by disrupting the Chinese Communist Party’s (CCP) exploitation of critical U.S. intellectual property (IP) and dual-use technologies, including AI, biotechnologies, quantum, semiconductor, and space technologies, through research security, cybersecurity and IP protection training. As the programmatic lead for the Foundational Infrastructure for the Responsible Use of Small Modular Reactor [SMR] Technology (FIRST) program, CTR implements Section 8(e) of EO 14299 on Deploying Advanced Nuclear Reactor Technologies for National Security by helping U.S. vendors deploy secure, safe U.S. SMRs to strategic regions, including Latin America, the Indo-Pacific, and the Middle East, to outcompete strategic competitors for decades-long partnerships, generating multi-billion dollar deals for U.S. companies and creating thousands of American jobs. CTR implements maximum pressure on Iran (NSPM-2), by training foreign partner countries to implement U.S. sanctions on Iran’s nuclear weapons and ballistic missile programs, and disrupts proliferation networks tied to the CCP, DPRK, and Russia that undermine U.S. interests.

Synopsis

The Office of Cooperative Threat Reduction (CTR) is a key component of the Department’s and ACN’s efforts to advance the Administration’s top national security and foreign policy objectives in a cost-effective and impactful manner. CTR uses programming and training with foreign partners to advance President Trump’s America First Investment Policy (NSPM-3) and America’s AI Action plan by disrupting the Chinese Communist Party’s (CCP) exploitation of critical U.S. intellectual property (IP) and dual-use technologies, including AI, biotechnologies, quantum, semiconductor, and space technologies, through research security, cybersecurity and IP protection training. As the programmatic lead for the Foundational Infrastructure for the Responsible Use of Small Modular Reactor [SMR] Technology (FIRST) program, CTR implements Section 8(e) of EO 14299 on Deploying Advanced Nuclear Reactor Technologies for National Security by helping U.S. vendors deploy secure, safe U.S. SMRs to strategic regions, including Latin America, the Indo-Pacific, and the Middle East, to outcompete strategic competitors for decades-long partnerships, generating multi-billion dollar deals for U.S. companies and creating thousands of American jobs. CTR implements maximum pressure on Iran (NSPM-2), by training foreign partner countries to implement U.S. sanctions on Iran’s nuclear weapons and ballistic missile programs, and disrupts proliferation networks tied to the CCP, DPRK, and Russia that undermine U.S. interests.

Eligibility

Eligible Applicants:
Others (see text field entitled "Additional Information on Eligibility" for clarification)
U.S. for-profit organizations or businesses; U.S.-based non-profit/non-governmental organizations with or without 501(c) (3) status of the U.S. tax code; U.S.-based private, public, or state institutions of higher education; foreign-based non-profit organizations/non-government organizations (NGO); Federally Funded Research and Development Centers (FFRDCs); Public International Organizations (PIO) ; Foreign Public Entities (FPE); and foreign-based institutions of higher education.

Funding Activity Categories

Other (see text field entitled "Explanation of Other Category of Funding Activity" for clarification)

CFDA Numbers

  • 19.033 - Global Threat Reduction

Contact Information

Agency: Bureau of International Security-Nonproliferation
Contact: Bureau of International Security-Nonproliferation
Phone: 703-516-1684
ACN-CTR-ProposalReview@state.gov

Additional Information

Document Type: synopsis
Opportunity Category: Discretionary
Version: 2
Last Updated: Jan 08, 2026 01:37:59 PM EST

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