NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

HHS-NIH11 PA-27-100
Posted: May 28, 2026 12:00:00 AM EDT
Closes: 04/05/2027

Description

The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace. The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product.

Synopsis

The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace. The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product.

Eligibility

Eligible Applicants:
Small businesses
Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Funding Activity Categories

Health

CFDA Numbers

  • 93.068 - Chronic Diseases: Research, Control, and Prevention
  • 93.070 - Environmental Public Health and Emergency Response
  • 93.073 - Birth Defects and Developmental Disabilities - Prevention and Surveillance
  • 93.083 - Prevention of Disease, Disability, and Death through Immunization and Control of Respiratory and Related Diseases
  • 93.084 - Prevention of Disease, Disability, and Death by Infectious Diseases
  • 93.103 - Food and Drug Administration Research
  • 93.113 - Environmental Health
  • 93.121 - Oral Diseases and Disorders Research
  • 93.136 - Injury Prevention and Control Research and State and Community Based Programs
  • 93.142 - NIEHS Hazardous Waste Worker Health and Safety Training
  • 93.143 - NIEHS Superfund Hazardous Substances_Basic Research and Education
  • 93.172 - Human Genome Research
  • 93.173 - Research Related to Deafness and Communication Disorders
  • 93.213 - Research and Training in Complementary and Integrative Health
  • 93.233 - National Center on Sleep Disorders Research
  • 93.242 - Mental Health Research Grants
  • 93.273 - Alcohol Research Programs
  • 93.279 - Drug Use and Addiction Research Programs
  • 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health
  • 93.307 - Minority Health and Health Disparities Research
  • 93.313 - NIH Office of Research on Women's Health
  • 93.326 - Strengthening Public Health through Surveillance, Epidemiologic Research, Disease Detection and Prevention
  • 93.350 - National Center for Advancing Translational Sciences
  • 93.351 - Research Infrastructure Programs
  • 93.361 - Nursing Research
  • 93.393 - Cancer Cause and Prevention Research
  • 93.394 - Cancer Detection and Diagnosis Research
  • 93.395 - Cancer Treatment Research
  • 93.837 - Cardiovascular Diseases Research
  • 93.838 - Lung Diseases Research
  • 93.839 - Blood Diseases and Resources Research
  • 93.840 - Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
  • 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research
  • 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research
  • 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders
  • 93.855 - Allergy and Infectious Diseases Research
  • 93.859 - Biomedical Research and Research Training
  • 93.865 - Child Health and Human Development Extramural Research
  • 93.866 - Aging Research
  • 93.867 - Vision Research
  • 93.879 - Medical Library Assistance

Contact Information

Agency: National Institutes of Health
Contact: National Institutes of Health
Phone: 301-402-2541
NIH SEED (Small business Education and Entrepreneurial Development)
SEEDinfo@nih.gov

Additional Information

Document Type: synopsis
Opportunity Category: Discretionary
Version: 2
Last Updated: Jun 01, 2026 12:56:55 PM EDT

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