GREGoRi Innovation Projects (U01 Clinical Trial Optional)
Posted: Jun 18, 2026 12:00:00 AM EDT
Closes: 10/30/2026
Funding Information
Estimated Total Funding
$7,500,000
Award Ceiling
$500,000
Award Floor
$3
Expected Number of Awards
10
Description
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
Synopsis
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
Eligibility
Eligible Applicants:
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Funding Activity Categories
CFDA Numbers
- 93.172 - Human Genome Research
Contact Information
Agency: National Institutes of Health
Contact: National Institutes of Health
Email: nhgri-gregor@mail.nih.gov
Phone: 301-402-2541
GREGoRi Program Team
nhgri-gregor@mail.nih.gov
nhgri-gregor@mail.nih.gov
Additional Information
Document Type: synopsis
Opportunity Category: Discretionary
Version: 1
Last Updated: Jun 18, 2026 02:11:37 PM EDT
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